KMID : 0895820170270010053
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Journal of Oriental Rehabilitation Medicine 2017 Volume.27 No. 1 p.53 ~ p.65
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A Study on Safety Assessment and VAS Change Observation Before and After Non-toxic Bee Venom Treatment in Pain Patients Using Questionnaire: Retrospective Chart Review
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Hwang Yun-Kyeong
Jung Taek-Geun Cho Sung-Woo Kim Won-Ill
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Abstract
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Objectives : The purpose of this study is to evaluate the safety of Non-toxic bee venom (BV) and observe VAS change before and after Non-toxic BV treatment in pain patients.
Methods : We surveyed the clinical practitioners who treated with Non-toxic BV in pain patients who visited the Korean medical clinic. The questionnaire survey was conducted for clinical practitioners who agreed to participate after hearing the explanation for the purpose and characteristics of the questionnaire. Patients in the questionnaires were reviewed based on their medical records from July 1, 2016 to October 28, 2016.
Results : We received 445 cases and selected 403 cases finally. 2 cases, however, were not able to continue treatment for 3 weeks and were eliminated. Depending on when the pain occurred, we divided the 401 cases into three groups (Acute, Subacute, Chronic group). In all groups, VAS scores were significantly decreased after treatment. Adverse reactions following Non-toxic BV treatment had occurred was 16 cases (3.60%). Except for 3 cases with hives, most of adverse reactions were mild or moderate and were not in need of extra treatment. The total safety of treatment for 3 weeks was mostly safe. The number of cases discontinued treatment was 42 cases (9.44%). Most of these cases, treatment was stopped for personal reason unrelated to the Non-toxic BV treatment.
Conclusions : These results suggest that the Non-toxic BV treatment has no serious adverse reactions and is a relatively safe treatment. Further studies are needed to prove the efficacy and clinical safety of Non-toxic BV treatment.
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KEYWORD
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Non-toxic bee venom, Clinical safety, VAS change
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